Abstract: Amplitude damping noise exists in many practical qubit systems with the loss of energy. The presentation of quantum Kraus operators of two-qubit system in amplitude damping channel is derived by using a common model in which two atoms are interacting with a single mode cavity resonantly. It provides a method by which concrete progress can be made on problems related to quantum information processing. Owning to its generality and convenience, this means is helpful to deal with real physical problems.