J4 ›› 2009, Vol. 26 ›› Issue (5): 631-635.

• Laser Applications • Previous Articles     Next Articles

Research of change in radio-frequency damage of hemoglobin oxygen saturation (SO2) of rat’s brain tissue

Qu Ben1, QIAN Zhi-Yu1, MAO Wen-Lan1, Zhang Zheng-Xiong2   

  1. 1Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016;
    2 Department of Neurosurgery, Zhongda Hospital, Southeast University, Nanjing 210009
  • Published:2009-09-28 Online:2009-08-27

Abstract:

During the neurosurgery brain damage surgery, the region of the target’s physiological parameters real-time monitoring is very important. There isn’t a credible method on real-time evaluation rule at present. We will do some elementary research in this aspect. We choose SD rats as experiment object. We damage the target of treatment local of rats brain with radio-frequency, and use of minimally invasive Near-infrared technology measure hemoglobin oxygen saturation on real-time. We study the changes in the process of radio-frequency damage. We studies the different changes of hemoglobin oxygen saturation appearance in reversible damage and irreversible damage. At the same time, we find out some basic law on the analysis a large number of experiment parameters. The results have some efficacy of certain reference value in future damage of stereotactic radio-frequency real-time assessment.

Key words: medical optics and biotechnology, radio-frequency damage, hemoglobin oxygen saturation (SO2) , reversible damage, near-infrared