Theoretical and experimental investigation on high sensitivity oscillating field biosensor

Abstract

Abstract:

A novel oscillating field biosensor was proposed utilizing ultrahigh-order modes excitated in a symmetrical metal cladding waveguide (SMCW). Different from the conventional biosensors, such as surface plasmon resonance sensor (SPRS), leaky mode waveguide sensor (LWS) and reverse symmetry waveguide sensor (RSWS), the sample is placed inside the guiding layer. Since the guiding layer supports a high intensity oscillating field, the intensity of output light is rather sensitive to the tiny variation of refractive index, which leads to very high sensitivity and resolution. Based on the noise level, 1ppm variation of the glucose solution has been detected in our experiment. The proposed scheme is expected to have a wide application and promising future in various biomedical detections.

Key words: waveguide optics, ultrahigh-order mode, sensitivity, biosensor

CLC Number:

TN253

XIAO Ping-ping, HU Hong-wu, YIN Cheng, CAO Zhuang-qi . Theoretical and experimental investigation on high sensitivity oscillating field biosensor[J]. J4, 2011, 28(2): 197-201.

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Theoretical and experimental investigation on high sensitivity oscillating field biosensor

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