A preliminary theoretical simulation of Hadamard transform of ion mobility spectrometry

Abstract

Abstract: Theoretically, the sampling rate of HT-IMS spectra was optimized by changing the sampling data points. By adding white noise of simulation, the effect of improving the SNR of the spectra of the approach and its influence on the resolution were analysed. Preliminary results show that it could retrieve the IMS spectra by sampling at least 8 data points within a single ion gate width of 0.4 ms. The SNR of the spectra using Hadamard transform approach is 15.8 times as large as that of conventional IMS spectra, as well is 4.6 times as large as that of the spectra acquired by averaging multiple conventional spectra with the same sampling time.The transformational process has no obvious influence on the resolution of the IMS spectra.The simulation of Hadamard transform IMS not only provides theoretical evidences to choosing and optimizing sampling rate and so on, but also establishs the software foundation for next experimental control and transformation.

Key words: spectroscopy, ion mobility spectrometry, Hadamard transform, theoretical simulation, SNR

CLC Number:

O657
TN911

FANG Ying-lan, NIU Wen-qi, SHEN Cheng-yin, LIU sheng, HUANG Chao-qun, WANG Hong-mei, JIANG Hai-he, CHU Yan-nan. A preliminary theoretical simulation of Hadamard transform of ion mobility spectrometry[J]. J4, 2013, 30(5): 524-529.

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