J4 ›› 2015, Vol. 32 ›› Issue (6): 641-647.

• 综述 •    下一篇

光谱及光谱成像技术在生物医学领域应用简介

于翠荣,王新全,齐敏珺,夏玮玮   

  1. 青岛市光电工程技术研究院,山东 青岛 266109
  • 收稿日期:2014-11-27 修回日期:2015-02-06 出版日期:2015-11-28 发布日期:2015-11-05
  • 通讯作者: 于翠荣(1984-),女,山东菏泽人,硕士,工程师,研究方向为光谱及光谱成像技术应用。 E-mail:yucr@qdaoe.cn
  • 基金资助:

    中科院院地合作局(201201)资助项目

Brief Introduction to Spectral and Spectral Imaging Technology’s Application in Biomedicine

YU Cui-rong, WANG Xin-quan, QI Min-jun, XIA Wei-wei   

  1. Qingdao Academy for Opto-Electronics Engineering, Qingdao 266109, China
  • Received:2014-11-27 Revised:2015-02-06 Published:2015-11-28 Online:2015-11-05

摘要:

光谱技术和光谱成像技术因其可以获取观测目标的化学组分信息,在生物医学领域具有极广阔的应用前景。介绍了光谱及光谱成像技术在生物医学领域七种应用的最新进展。其中,荧光多标记共定位、染色体核型分析及眼底病变检测技术已成熟,并已进入临床应用;光谱成像癌变检测、生物芯片检测、无损血糖检测及拉曼癌变检测四类应用虽然临床意义重大,但因检测精度较低或普适性较差等原因,处于发展初期阶段,仍需开展进一步研究。

关键词: 光谱学, 生物医学应用, 光学检测, 光谱成像

Abstract:

Spectroscopy Technology and spectral imaging technology have very broad application prospects in the biomedical field because of their obtainment of target's chemical composition information. Latest development of seven applications of spectra and spectral imaging technology in biomedical field were introduced. Among them, applications of fluorescent multi-label colocalization, spectral karyotying and ocular pathology diagnosis are matured and have been used clinically. Although with clinical significance, applications of spectral imaging cancer detection, bio-chip testing, nondestructive glucose and Raman cancer detection are still in the early stages of development. Because above applications have lower accuracy of detection or poorer universality, and they still need further research.

Key words: Spectroscopy, Biomedical Application, Optical Detection, Spectral Imaging

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